（ 研究業績 ） output

すべて 論文

  • 47. Combined nano cancer immunotherapy based on immune status in a tumor microenvironment.

    Nakamura T*, Kawakami K, Nomura M, Sato Y, Hyodo M, Hatakeyama H, Hayakawa Y, Harashima H*.
    J Control Release 345: 200-213 (2022).

    DOI : 10.1016/j.jconrel.2022.03.026.

    論文

  • 46. Glucosylceramide in T cells regulates the pathology of inflammatory bowel disease.

    Komuro M, Nagane M*, Endo R, Nakamura T, Miyamoto T, Niwa C, Fukuyama T, Harashima H, Akihara N, Kamiie J, Suzuki R, Yamashita T.
    Biochem Biophys Res Commun 599: 24-30 (2022).

    DOI : 10.1016/j.bbrc.2022.02.004.

    論文

  • 45. Intravenous liposomal vaccine enhances CTL generation, but not until antigen presentation.

    Nakamura T*, Haloho SEE, Harashima H*.
    J Control Release 343: 1-12 (2022).

    DOI : 10.1016/j.jconrel.2022.01.020.

    論文

  • 44. The hydrophobic tail of a pH-sensitive cationic lipid influences siRNA transfection activity and toxicity in human NK cell lines.

    Nakamura T*, Nakade T, Yamada K, Sato Y, Harashima H*.
    Int J Pharm 609: 121140 (2021).

    DOI : 10.1016/j.ijpharm.2021.121140.

    論文

  • 43. STING agonist loaded lipid nanoparticles overcome anti-PD-1 resistance in melanoma lung metastasis via NK cell activation.

    Nakamura T*, Sato T (equal contribution to 1st author), Endo R, Sasaki S, Takahashi N, Sato Y, Hyodo M, Hayakawa Y, Harashima H*.
    J Immunother Cancer 9: e002852 (2021).

    DOI : 10.1136/jitc-2021-002852.

    論文

  • 42. Lipid nanoparticles fuse with cell membranes of immune cells at low temperatures leading to the loss of transfection activity.

    Nakamura T*, Yamada K, Sato Y, Harashima H*.
    Int J Pharm 587: 119652 (2020).

    DOI : 10.1016/j.ijpharm.2020.119652.

    論文

  • 41. Distribution of BCG-CWS loaded nanoparticles in the spleen after intravenous injection affects cytotoxic T lymphocyte activity.

    Masuda H, Nakamura T* (equal contribution to 1st author), Harashima H*.
    J Pharm Sci 109: 1943-1950 (2020).

    DOI : 10.1016/j.xphs.2020.02.007.

    論文

  • 40. Vitamin E Scaffolds of pH-Responsive Lipid Nanoparticles as DNA Vaccines in Cancer and Protozoan Infection.

    Maeta M, Miura N, Tanaka H, Nakamura T, Kawanishi R, Nishikawa Y, Asano K, Tanaka M, Tamagawa S, Nakai K, Tange K, Yoshioka H, Harashima H, Akita H*.
    Mol Pharm 17: 1237-1247 (2020).

    DOI : 10.1021/acs.molpharmaceut.9b01262.

    論文

  • 39. The effect of size and charge of lipid nanoparticles prepared by microfluidic mixing on their lymph node transitivity and distribution.

    Nakamura T*, Kawai M, Sato Y, Maeki M, Tokeshi M, Harashima H*.
    Mol Pharm 17: 944-953 (2020).

    DOI : 10.1021/acs.molpharmaceut.9b01182.

    論文

  • 38. The silencing of indoleamine 2,3-dioxygenase 1 (IDO1) in dendritic cells by siRNA-loaded lipid nanoparticles enhances cell-based cancer immunotherapy. Sci Rep 9: 113335 (2019).

    Endo R, Nakamura T* (equal contribution to 1st author), Kawakami K, Sato Y, Harashima H*.
    Sci Rep 9: 113335 (2019).

    DOI : 10.1038/s41598-019-47799-w.

    論文